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Whey Protein Isolate: The 10 Best Selling Brands in 2023

Everyone knows how protein acts as an essential nutrient for the human body. This protein intake is sometimes lacking in our daily diet. In such cases, to meet our protein requirements, we use protein powder for the needs of our bodies. Apart from all your hard work in the gym, this helps to boost your performance and build muscle.

So, why whey protein isolates in the first place? It is because it contains all the amino acids that are essential for muscle growth and recovery.

Walking through any supplement store, you will find various whey protein isolates from various brands.

Today, we have focused on the list of The Top 10 Whey Protein Isolates in the United States to identify proteins that provide the greatest benefits.

Difference – Whey and Whey Isolate

  • Whey powder is popularly used in making protein shakes that help with muscle growth or recovery. It is also used as a meal replacement, so you can skip a particular meal of the day. So, instead of taking one whole meal, you can opt for a protein shake that will add value to your diet.
  • Sometimes, you might come across the terms “whey” and “whey isolate.” But what makes them different from one another?

What is whey?

  • Whey comes in liquid form and is part of the dairy industry. It is usually formed from cheese-making production. The composition of the whey is made from 93% water and 50% solid milk. The texture of whey protein is thin and watery. This liquid form is pasteurized by manufacturers to form whey powder. With this, they are involved in making three different whey products. This includes:
    • Whey Protein Concentrate
    • Whey Protein Isolate
    • Whey Protein Hydrolysate
whey protein

What is whey isolate?

  • The purest form of whey can be enjoyed as a supplement to boost your fitness level. It is essentially used to build strong muscles and stimulate muscle growth. It is processed to lower the fat and lactose content. As a result, it contains only protein. Therefore, it is good for people who are allergic to milk and milk products. It works as a great alternative protein for lactose-intolerant people.

Protein Content: 90%
Process: Made directly from whey.
Fat/Carbohydrates: 1-2%
Sugar Content Is Low
Whey type: highly processed
Price: Expensive

whey isolate

What are its benefits?

  • Whey protein isolates can be beneficial in several ways. This includes:
    • Whey protein isolates contain essential amino acids that help in building lean muscle. If you want to build strong muscles, add whey protein isolate to your diet. 
    • It contains a great number of healing elements that help to heal from surgery. It also helps in healing skin issues faster and quicker.
    • If you lack muscle growth, whey protein isolates help with muscle gain faster. Therefore, it’s good for weight gain. 
    • Whey protein isolate is a healthy nutritional supplement that adds essential protein to your diet. So, with Whey Protein Isolate, you can fill the nutrient gap lacking in your diet. 
    • It contains 9 essential amino acids that help develop new immune cells for your body.
    • Whey Protein Isolate is often premade and easy to mix without forming lumps in the solution.

What are its drawbacks?

  • Many whey protein isolates consist of added sugar to improve the product’s taste. However, some people want to avoid adding sugar or artificial flavors to their products. They prefer the natural version of the product. So, check the product label to find the sugar content of processed ingredients.
    • Consuming whey protein isolate in moderation is important to prevent sudden weight gain. Some products contain high-calorie content, which might affect your weight management program. Read the product label to understand the calorie percentage. 
    • It may be difficult to digest if you are allergic to milk products. This may further upset your stomach. In such cases, you must look for a plant-based protein powder to prevent such issues. 
    • Regarding regulation, whey protein isolates are not regulated by FDA safety measures. They might contain fillers, metal containment, or impurities. You must look for products tested and verified under NSF Certified for sports.

Top 11 Whey Protein Isolates in USA

Impact Whey Isolate Protein Powder by Myprotein®

  • If you long for an active lifestyle, Myprotein Impact Whey Isolate Protein Powder can help you achieve your desired goal. It is one of the purest whey protein isolate powders available on the market and contributes 90% protein to your diet.
  • It is a UK brand that goes through an expert purifying process to ensure quality protein for its users. It also contains only 1% fat, which is highly beneficial for people looking for low-fat products. It has essential amino acids that help in performance growth and recovery. So, you are in safe hands with Myprotein Impact Whey Isolate Protein Powder.


  • Fat – 1%
  • Protein – 90%.
  • 5g of BCAAs
  • Glutamine 5g
Impact Whey Isolate Protein Powder by Myprotein
  • Pros
    • This protein powder is made from the purest whey isolate.
    • It contains essential amino acids.
    • Inexpensive
    • Tested and verified by experts.
    • Gluten-free
    • 100% vegetarian
    • Mixes well.
  • Cons
    • Does not taste good.
    • Most artificial flavors are available.
  •  Product Weight: 2.2 pounds, Price: $54.98, Rating: 4.4/5

Whey Isolate XTEND PRO

  • XTEND Pro is an unusual pro-whey isolate that contains more than 50% essential amino acids compared to other whey protein isolates on the market. It is a health supplement brand owned by Scivation. Apart from its essential nutrients, it also contributes to the product’s taste.
  • Also, being high in BCAAs aids in stimulating muscle protein synthesis. A tasty and cholesterol-free whey protein isolate that has given perfect recovery since 2004. If you plan to build muscle and strength, XTEND Pro is the right answer. It is formulated with 100% protein isolate and works for muscle recovery, strength, and retention.
Whey Isolate XTEND PRO
  • Features
    • BCAAs (7g)
    • It contains 25 g of high-quality protein.
    • It contains fewer than 150 calories per serving.
    • Contains 1 gram of fat
  • Pros
    • Cholesterol-free
    • Free of banned substances.
    • Research proves
    • NSF content was evaluated.
    • Five delectable flavors
    • Muscle recovery and growth should be maximized.
    • Gluten-free
  • Cons
    • It contains artificial sweeteners like sucralose and acesulfame potassium.
  • Product Weight: 1.8 pounds, Price: $25-$30, Rating: 4.4/5     

Whey Protein Isolate Nutricost

  • It’s a high-quality whey protein isolate that provides an active lifestyle for everybody. It combines all the rich flavors to enhance the taste of the product. It maintains high standards and quality that are carefully formulated under expert guidance. More interestingly, all their supplement products are manufactured in GMP-compliant facilities.
  • So, you are getting the best out of it. Also, all the ingredients are checked, tested, and verified to ensure maximum quality. In addition to this, it mixes well, tastes good, and works efficiently.
  • Features
    • Each serving contains 30g of protein (unflavored).
    • FDA-approved facility
    • Manufactured in a GMP-compliant facility.
    • Per serving, there is no added sugar.
    • Each serving contains 105mg of calcium.
Whey Protein Isolate Nutricost
  • Pros
    • Lactose-free
    • High-quality isolate
    • Non-GMO
    • Gluten-free
    • It goes through Cross-Flow Microfiltration.
    • rBGH-Free
    • High in essential amino acids
    • Five delectable flavors
  • Cons
    • The product contains artificial sweeteners like sucralose that might harm your health and body.
  • Product Weight: 2 Pounds, Price: $35.95, Rating: 4.6/5     

Body Fortress Isolate Protein

The Super Advanced 100% Protein Isolate by Body Fortress is a high-protein supplement that uses ultra-pure isolate to build lean muscle. Most interestingly, it is a whey blend that contributes higher levels of whey concentrate than isolate. However, when it is higher in concentration, it means more calories and more carbs.

When it comes to its mixing part, it does not mix well with water or milk. As a result, the protein powder clumps. It has a high level of BCAAs and provides the greatest strength to the body.

The Body Fortress Isolate Protein
  • Features
    • A double scoop contains 60g of protein.
    • 30g of protein per serving.
    • 1 gram of sugar
    • 12g of BCAA’s per two scoops
    • 6g of BCAAs per scoop.
  • Pros
    • Gluten-free
    • Low in fat
    • Isolate completely pure blend
    • Reduced cholesterol and carbohydrate intake
    • Zero aspartame
    • Improve your post-workout recovery.
    • It helps to build lean muscle and strength.
  • Cons
    • The product contains artificial sweeteners like sucralose, acesulfame potassium, and maltodextrin.
    • Chalky texture
    • Not Keto-friendly
    • does not taste good.
  • Product Weight: 1.5 Pounds, Price: $34.36, Rating: 4.5/5     

Animal Whey Protein Isolate

The nutrition supplement is made from the highest-quality protein sources that are fast-absorbing and bio-available. Also, each scoop contains 25g of protein that works quickly and efficiently. Being a high-bioavailability protein, it helps to repair muscle tissue and eliminates post-workout stress from the body so you can hit the gym sooner.

Its super-fast digestive enzymes help to work quickly and efficiently. With Animal Whey Protein Isolate, you can have a clean profile to help you achieve your nutrition and fitness goals. It also fills the void left by a whole-food meal.

  • Features
    • Each serving contains 25g of protein.
    • made in a GMP facility.
    • Blend of digestive enzymes
    • Cross-flow micro filtrated
    • EAAs and BCAAs
Easily Digestible: Animal Whey Protein Isolate
  • Pros
    • Rich flavors
    • mix well.
    • No chunks
    • Fast-absorbing
    • There are eight delectable flavors.
    • Amazing taste profile.
    • There is no stomach bloating.
  • Cons
    • It contains artificial sweeteners like acesulfame potassium, one major turn-off for users.
    • It contains soy lecithin, which bodybuilders hate or avoid for fear that it will increase estrogen.
  •   Product Weight: 4 Pounds, Price: $73.95, Rating: 3/5    

Dymatize ISO 100 Whey Protein Isolate

  • Dymatize ISO 100 Whey Protein Powder with 25g of hydrolyzed 100% Whey Isolate gives you a proven amount of protein to gain muscle size and strength. It aims to work on your muscle size and strength. It also supports your keto diet by contributing 110–120 calories per serving. Hence, the product is used multipurpose: high-protein, keto, and low-carb diets.
  • You can also use this product to make your favorite recipe or high-protein shakes. Being low in fat can help you achieve your fitness goals. Therefore, you cannot miss your training day without Dymatize ISO 100 Whey Protein Isolate.
Dymatize ISO 100 Whey Protein Isolate 1
  • Features
    • The protein content of 25g
    • 5 BCAAs
    • 7g of leucine.
    • 23 servings
    • 4g of glutamine.
  • Pros
    • Fast-absorbing
    • Scientifically formulated
    • Keto-friendly
    • Gluten-free
    • Super-easing mixing
    • It involves a multi-step purification process.
    • There are 12 delectable flavors to choose from.
    • 100% whey protein isolate.
  • Cons
    • Fast-absorbing
    • Contains artificial sweeteners like sucralose and steviol glycosides.
  •   Product Weight: 1.6 pounds, Price: $29.99, Rating: 4.7/5    

Whey Protein Isopure Isolate

  • With Isopure Whey Isolate Protein Powder, you can get a low-carb and keto-friendly diet. These products are best suited for runners, trainers, professionals, and others. Isopure uses premium ingredients you know you can trust. In addition to this, it is combined with a two-ingredient profile that includes whey protein isolate and soy lecithin.
  • With its low-carb option, it makes life far easier to shed that excess weight and fight against various health problems. This includes improving blood pressure and the immune system and managing cholesterol levels. So, with Isopure, you can meet your daily protein needs.
  • Features
    • 100% whey protein isolate.
    • Profile of two ingredients
    • The protein content of 25g
    • Multipurpose usage
Whey Protein IsopureIsolate
  • Pros
    • There are no carbs, fats, or sugars.
    • Keto-friendly
    • No added colors and flavors.
    • No artificial sweeteners.
    • Protein can be added to any recipe or smoothie for extra protein.
    • Gluten-free
    • Lactose-free
    • It forms a creamy and smooth texture.
    • Ready-to-drink protein beverage
  • Cons
    • Isopure Whey Isolate Protein Powder is unlikely to have negative feedback from customers and researchers.
  •   Product Weight: 1 Pound, Price: $24.98 Rating: 4.4/5    

Optimum Nutrition Whey Protein Isolate

  • Optimum Nutrition Whey Protein Isolate is widely known for its effects and mixability. This product can give you the optimal result if you aim for weight loss. It is ideally suitable for both men and women. Over the past years, the brand has had a long track record of creating stellar, effective supplements. The brand also has a good track record with third-party testers.
  • This protein supplement is best used for building muscle growth and strength. It is ideally consumed post-workout to support a lean physique. It comes in various flavors, including double-rich chocolate, chocolate bliss, rich vanilla, and chocolate ice cream.
Optimum Nutrition Whey Protein Isolate
  • Features
    • Each serving contains 25g of protein.
    • 1 gram of dietary fat
    • 5g of BCAAs found in nature
    • 1 teaspoon of sugar
  • Pros
    • It helps in muscle support and recovery.
    • 100% vegan
    • Gluten-free
    • Tested for prohibited substances
    • Mixes well.
    • The best applications are strength training, an active lifestyle, and sports performance.
    • No artificial growth hormones
  • Cons
    • Artificially flavored
    • It contains artificial sweeteners like sucralose and acesulfame potassium.
    • It tastes a little too sweet.
  •   Product Weight: 5 Pounds Net Quantity: 5 lb Price: $105 Rating: 4.6/5    

Now Whey Protein Isolate

  • In Now Whey Protein Isolate, the whey is completely in a processed form that helps to lower the fat and lactose content of the protein. It is one of the great isolate powders with no artificial flavors or colors. Hence, it is easy on the stomach. You will also get various flavors to prepare recipes or smoothies.
  • It provides the best result for all types of bodies. In addition to this, it contains vitamins, minerals, and other essential nutrients necessary for optimal health. It also contains high-quality protein that is both absorbable and digestible for the body. It is naturally rich in BCAAs, which makes it ideal for active individuals.
  • Features
    • Each serving contains 25g of protein.
    • Protein Isolate with BCAAs
    • GMP Certified
    • laboratory-verified and tested
The Now Whey Protein Isolate
  • Pros
    • 100% high-quality protein. “
    • Test for prohibited substances
    • Soy-free
    • Every batch is tested and verified for potency and safety.
    • It is both bioavailable and digestible.
    • It is best used as a pre-workout essential.
  • Cons
    • The product is unlikely to have any negative feedback and is thus extremely safe to use with high-quality standards.
  •   Product Weight: 5 Pounds, Price: $62.94, Rating: 4.5/5    

Opportunities for Grass-Fed Whey Protein Isolate

  • It is a popular health supplement brand that is available in a wide variety of flavors and sizes. It is free from artificial sweeteners, GMOs, and gluten to promote a healthy lifestyle. Here, the protein powder is made from grass-fed Wisconsin cow’s milk.
  • You will get about 90% pure proteins if you opt for the unflavored version. Other than this, its dietary supplement helps increase protein intake in the diet. So, it has great nutritional value for all types of bodies. The product also contains 9 distinct amino acids that aid in muscle growth, blood pressure control, building strength, and others.
Opportunities for Grass-Fed Whey Protein Isolate
  • Features
    • 28g of protein per serving.
    • Made with only two ingredients
    • 0g sugar
    • It contains 99% pure grass-fed whey protein isolate.
  • Pros
    • Completely pure protein
    • Keto-friendly
    • No artificial flavor.
    • It uses organic cane sugar.
    • Gluten-free
    • Non-GMO
    • is easy to mix.
    • Multipurpose usage
    • It helps with healthy weight management.
  • Cons
    • Not fast-absorbing or easily digested.
  •   Price: $25.00 Product Weight: 1 pound    


There you go with the list of the 10 best whey protein isolates to buy in the USA. This article will help you best understand which whey protein isolate ideally suits your requirements to achieve your fitness goals.


Is whey protein isolate suitable for vegetarians and vegans?

Whey Protein Isolate is suitable for vegetarians. However, if you are a vegan, it is unsuitable. It is because it is obtained from milk.

How do I know if the protein I use is of good quality?

It is always recommended to check the labels of products that contain a minimum of 90% protein per serving. Usually, unflavored protein powder contains the purest form of whey protein isolate.

What happens if you take too much protein?

The intake of too much protein can lead to increased body fat. As a result, it will lead to weight gain over time.

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